Jung-Ae Kim Selected Research

Sunitinib (Sutent)

5/2023	Antitumor effect of 3-(quinolin-2-ylmethylene)-4,6-dimethyl-5-hydroxy-7-azaoxindole down-regulating the Gas6-Axl axis.
10/2018	Antitumor activity of BJ-1207, a 6-amino-2,4,5-trimethylpyridin-3-ol derivative, in human lung cancer.
10/2017	Dual Inhibition of NOX2 and Receptor Tyrosine Kinase by BJ-1301 Enhances Anticancer Therapy Efficacy via Suppression of Autocrine-Stimulatory Factors in Lung Cancer.
6/2016	5-Hydroxy-7-azaindolin-2-one, a novel hybrid of pyridinol and sunitinib: design, synthesis and cytotoxicity against cancer cells.

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Jung-Ae Kim Research Topics

Disease

54	Neoplasms (Cancer) 04/2024 - 01/2002
27	Inflammation (Inflammations) 01/2023 - 02/2006
21	Breast Neoplasms (Breast Cancer) 04/2024 - 09/2008
19	Colitis 01/2021 - 11/2008
14	Hypoxia (Hypoxemia) 11/2023 - 09/2008
14	Inflammatory Bowel Diseases (Inflammatory Bowel Disease) 01/2021 - 06/2008
12	Hepatocellular Carcinoma (Hepatoma) 01/2023 - 12/2002
9	Colonic Neoplasms (Colon Cancer) 10/2018 - 06/2006
6	Neoplasm Metastasis (Metastasis) 08/2023 - 01/2011
6	Body Weight (Weight, Body) 01/2021 - 10/2003
5	Weight Loss (Weight Reduction) 01/2021 - 11/2008
5	Lung Neoplasms (Lung Cancer) 01/2021 - 01/2015
5	Neuroblastoma 01/2009 - 01/2002
4	Infections 09/2023 - 10/2006
4	Triple Negative Breast Neoplasms 01/2018 - 11/2016
3	Prostatic Neoplasms (Prostate Cancer) 08/2023 - 01/2021
3	Edema (Dropsy) 01/2021 - 02/2006
3	Colorectal Neoplasms (Colorectal Cancer) 12/2020 - 02/2011
3	Obesity 01/2020 - 10/2009
3	Anaphylaxis (Anaphylactic Shock) 09/2019 - 01/2017
3	Carcinoma (Carcinomatosis) 05/2012 - 05/2006
3	Pathologic Neovascularization 02/2011 - 04/2009
2	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 09/2021 - 01/2018
2	Glioblastoma (Glioblastoma Multiforme) 01/2021 - 04/2008
2	Necrosis 12/2020 - 11/2014
2	Hypertension (High Blood Pressure) 04/2017 - 11/2011

Drug/Important Bio-Agent (IBA)

14	Reactive Oxygen Species (Oxygen Radicals)IBA 10/2018 - 12/2002
12	Proteins (Proteins, Gene)FDA Link 03/2023 - 06/2007
11	Peroxidase (Myeloperoxidase)IBA 01/2021 - 11/2008
11	CytokinesIBA 01/2021 - 02/2008
10	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 01/2023 - 02/2008
10	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 12/2017 - 09/2008
7	Small Interfering RNA (siRNA)IBA 04/2024 - 07/2010
7	AntioxidantsIBA 01/2021 - 07/2004
7	NADPH Oxidases (NAD(P)H oxidase)IBA 10/2018 - 04/2004
6	Tamoxifen FDA LinkGeneric 04/2024 - 08/2009
6	Dextran SulfateIBA 01/2021 - 01/2017
6	EnzymesIBA 01/2018 - 10/2003
5	Transcription Factors (Transcription Factor)IBA 11/2020 - 09/2008
5	Serotonin (5 Hydroxytryptamine)IBA 01/2017 - 04/2014
5	Sulfonic AcidsIBA 04/2014 - 11/2008
5	FlavonoidsIBA 03/2013 - 10/2008
5	NF-kappa B (NF-kB)IBA 11/2009 - 06/2008
4	Doxorubicin (Adriamycin)FDA LinkGeneric 04/2024 - 09/2008
4	Sunitinib (Sutent)FDA Link 05/2023 - 06/2016
4	Cisplatin (Platino)FDA LinkGeneric 05/2023 - 01/2015
4	Interleukin-8 (Interleukin 8)IBA 03/2023 - 11/2008
4	Matrix Metalloproteinases (MMPs)IBA 03/2023 - 07/2007
4	Phosphotransferases (Kinase)IBA 01/2023 - 02/2012
4	Interleukin-6 (Interleukin 6)IBA 01/2021 - 03/2012
4	AcidsIBA 08/2018 - 10/2016
4	ChemokinesIBA 02/2014 - 06/2008
4	Capsaicin (Zostrix)FDA Link 01/2005 - 01/2002
3	IntegrinsIBA 04/2024 - 07/2011
3	Oxygen (Dioxygen)IBA 11/2023 - 01/2017
3	AndrogensIBA 08/2023 - 01/2021
3	Gemcitabine FDA Link 05/2023 - 08/2015
3	Cadherins (E-Cadherin)IBA 03/2023 - 01/2018
3	serotonin 7 receptorIBA 10/2021 - 11/2016
3	pyridineIBA 09/2021 - 01/2018
3	2,4,5-trimethylpyridin-3-olIBA 01/2021 - 10/2018
3	CateninsIBA 10/2018 - 01/2015
3	matrigelIBA 01/2018 - 06/2015
3	Ethanol (Ethyl Alcohol)IBA 06/2014 - 10/2003
3	Cyclooxygenase 2 (Cyclooxygenase-2)IBA 02/2014 - 01/2007
3	Transcription Factor AP-1 (Transcription Factor AP 1)IBA 10/2012 - 08/2009
3	1- (1- hydroxy- 6,6,9- trimethyl- 6a,7,8,9,10,10a- hexahydro- 6H- benzo(c)chromen- 2- yl)ethanoneIBA 01/2012 - 07/2010
3	Clotrimazole (Lotrimin)FDA LinkGeneric 11/2008 - 09/2006
3	asiatic acidIBA 01/2007 - 12/2002
3	Poloxamer (Poloxamer 407)IBA 09/2006 - 08/2005
2	Chloride Channels (Chloride Channel)IBA 09/2023 - 09/2003
2	snake venom protein C activatorIBA 01/2023 - 06/2021
2	Sorafenib (BAY 43-9006)FDA Link 10/2022 - 12/2021
2	A-factor (Streptomyces)IBA 01/2021 - 05/2012
2	Mesalamine (Mesalazine)FDA LinkGeneric 01/2021 - 07/2014
2	BJ-1108IBA 01/2021 - 01/2016
2	Sulfasalazine (Azulfidine)FDA LinkGeneric 01/2021 - 07/2014
2	Biomarkers (Surrogate Marker)IBA 12/2020 - 10/2016
2	Histones (Histone)IBA 12/2020 - 07/2007
2	Lysine (L-Lysine)FDA Link 12/2020 - 01/2017
2	tofacitinibIBA 10/2020 - 04/2020
2	Estrogen ReceptorsIBA 04/2019 - 10/2012
2	Receptor Protein-Tyrosine Kinases (Tyrosine Kinase Receptors)IBA 01/2018 - 10/2017
2	cathepsin SIBA 01/2018 - 01/2017
2	Matrix Metalloproteinase 9 (Gelatinase B)IBA 01/2018 - 10/2008
2	Sirtuin 1IBA 01/2018 - 01/2017
2	Anti-Allergic Agents (Antiallergic Agents)IBA 01/2018 - 01/2017
2	LigandsIBA 10/2017 - 09/2009
2	Serotonin ReceptorsIBA 01/2017 - 04/2014
2	Hormones (Hormone)IBA 01/2017 - 11/2016
2	AMP-Activated Protein KinasesIBA 01/2017 - 06/2015
2	Tryptophan HydroxylaseIBA 01/2017 - 11/2016
2	tyrosine receptor (receptor, tyrosine)IBA 06/2016 - 02/2012
2	Antineoplastic Agents (Antineoplastics)IBA 06/2016 - 01/2016
2	Pyruvate KinaseIBA 08/2015 - 04/2015
2	Fluorouracil (Carac)FDA LinkGeneric 01/2015 - 05/2006

Therapy/Procedure

15	Therapeutics 03/2024 - 05/2005
8	Oral Administration 01/2021 - 10/2003
4	Drug Therapy (Chemotherapy) 11/2016 - 11/2004
2	Glycemic Control 01/2020 - 04/2017